ANALYSIS OF OPTICIN BINDING TO COLLAGEN FIBRILS IDENTIFIES A SINGLE BINDING SITE IN THE GAP REGION AND A HIGH SPECIFICITY TOWARDS THIN HETEROTYPIC FIBRILS CONTAINING COLLAGENS II, AND XI OR V/XI.

Analysis of opticin binding to collagen fibrils identifies a single binding site in the gap region and a high specificity towards thin heterotypic fibrils containing collagens II, and XI or V/XI.

Opticin is a class III member of the extracellular matrix small leucine-rich repeat protein/proteoglycan (SLRP) family found in vitreous humour and cartilage.It was first identified associated with the surface of vitreous collagen fibrils and several other SLRPs are also known to bind collagen fibrils and it some cases alter fibril morphology.The p

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Image-based metric heritage modeling in the near-infrared spectrum

Abstract Digital photogrammetry and spectral imaging are widely used in heritage sciences towards the comprehensive recording, understanding, and protection of historical artifacts and artworks.The availability of consumer-grade modified cameras for spectral acquisition, as an alternative to expensive multispectral sensors and multi-sensor apparatu

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Out-of-hospital cardiac arrest complicated by hyperthermia

Background: The aims top bar mega of this study were to establish epidemiology, clinical management and outcomes in cases of adult out-of-hospital cardiac arrest complicated by hyperthermia attended by the London Ambulance Service NHS Trust between January 2018 and December 2019.Where evidence is available in relation to this sub-set of cardiac arr

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